Their latest funding was raised on Apr 19, 2006 from a Series C round. Professor Toby Stuart and Senior Researcher Get information, directions, products, services, phone numbers, and reviews on Sirtris Pharmaceuticals in Collegeville, undefined Discover more Pharmaceutical Preparations companies in Collegeville on … Founded in 2004, Sirtris went public in May 2007 and continues as an independent discovery performance unit within GSK. London-based Glaxo said Tuesday it agreed to buy Sirtris in an all-cash tender offer at $22.50 a share. WhatsApp acquired by Facebook). ", "SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1", "Doubt on Anti-Aging Molecule as Resveratrol Trial Is Halted", "GlaxoSmithKline Halts All Further Development Of Resveratrol Drug SRT501", "GSK absorbs controversial 'longevity' company : News blog", "GlaxoSmithKline Shuts Down Sirtris, Five Years After $720M Buyout", https://en.wikipedia.org/w/index.php?title=Sirtris_Pharmaceuticals&oldid=968238491, Biotechnology companies of the United States, Creative Commons Attribution-ShareAlike License, This page was last edited on 18 July 2020, at 03:23. Should it create a nutraceuticals business in parallel to its effort to develop anti-aging therapeutics? Sirtris Pharmaceuticals, Inc. was founded in 2008. Conceived in 2004 by Harvard University biologist David Sinclair and serial entrepreneur Andrew Perlman,[1] and founded that year by Sinclair and Perlman, along with Christoph Westphal, Richard Aldrich, Richard Pops, and Paul Schimmel,[2] the company was focused on developing Sinclair's research into activators of sirtuins, work that began in the laboratory of Leonard P. Guarente where Sinclair worked as a post-doc before starting his own lab. CLAIM THIS BUSINESS. Major HBR cases concerns on a whole industry, a whole organization or some part of organization; profitable or non-profitable organizations. Should the company establish a proposed alliance with a pharmaceutical firm? Sirtris Pharmaceuticals From Wikipedia, the free encyclopedia Sirtris Pharmaceuticals, Inc. was a biotechnology company based in Cambridge, MA that developed therapies for type 2 diabetes, cancer, and other diseases. Describes a set of key strategic decisions facing the scientific founder and CEO of a promising, early stage bio-pharmaceuticals company. GlaxoSmithKline (GSK) has offered to buy all outstanding shares of Sirtris Pharmaceuticals for $22.50 a share. [15][16], In 2013 GSK shut down Sirtris and its development candidates were absorbed into GSK, where research and development continued. Find 424 listings related to Sirtris Pharmaceuticals Inc in Cambridge on YP.com. the FDA require that animals of both sexes be included in non-clinical studies? 481 - 490 of 500 . Sirtris Pharmaceuticals: Living Healthier, Longer by Toby Stuart , David Kiron , (No reviews yet) Write a Review PA. Collegeville. 1250 S COLLEGEVILLE RD COLLEGEVILLE, PA 19426 Get Directions (585) 275-5774. Business Info. See reviews, photos, directions, phone numbers and more for Sirtris Pharmaceuticals Inc locations in Cambridge, MA. For the biopharma industry investment, business development and competitive intelligence professionals who require information to support financing, partnering and licensing activities, BCIQ provides accurate information and context to support profitable and strategic decision making. Sirtris has generated a lot of hype because it is developing anti-aging drugs, some of which are based on resveratrol, a chemical in red wine. As followers of the drug industry know, GlaxoSmithKline famously paid $720 million to buy Sirtris Pharmaceuticals in 2008. [1], The company was specifically focused on resveratrol formulations and derivatives as activators of the SIRT1 enzyme; Sinclair became known for making statements about resveratrol like: “(It's) as close to a miraculous molecule as you can find.... One hundred years from now, people will maybe be taking these molecules on a daily basis to prevent heart disease, stroke, and cancer.”[1] Most of the anti-aging field was more cautious, especially with regard to what else resveratrol might do in the body and its lack of bioavailability. Sirtris Pharmaceuticals Inc Sirtris Pharmaceuticals, Inc. operates as a biopharmaceutical company. As followers of the drug industry know, GlaxoSmithKline famously paid $720 million to buy Sirtris Pharmaceuticals in 2008. And, should it in-license a second drug development candidate? Sirtris Pharmaceuticals is a biopharmaceutical company developing and commercializing novel therapeutics that modulate sirtuins, a recently discovered family of enzymes that promotes the body's natural defense against disease. Developer of proprietary, orally administrable, small molecule biopharmaceutical drugs intended to cure type 2 diabetes, cancer, and other diseases. Describes a set of key strategic decisions facing the scientific founder and CEO of a promising, early stage bio-pharmaceuticals company. Active, Closed, Last funding round type (e.g. Sirtris is the most high-profile shop working on sirtuins and resveratrol-like pharmacology, which subject has received a massive amount of … Rare, Progressive Disorder Caused by Mutation in DNA of Mitochondria Has No Known Treatments CAMBRIDGE, MA, USA | August 9, 2007 | Sirtris Pharmaceuticals, Inc. (NASDAQ: SIRT), a biopharmaceutical company focused on discovering and developing small molecule drugs to treat diseases of aging such as Type 2 Diabetes, today announced the initiation of a Phase 1b clinical trial … Sirtris Pharmaceuticals Presents Results of Studies of SIRT1 Activators at 6th Annual Metabolic Diseases Drug Discovery and Development World Summit, July 17, 2007 CAMBRIDGE, Mass.--(BUSINESS WIRE)--Jul 17, 2007 - Sirtris Pharmaceuticals, Inc. (NASDAQ: SIRT), a biopharmaceutical company focused on discovering and developing small molecule drugs to treat diseases of aging, … Whether any of those compounds are going to be tested on Parkinson’s disease is yet to be determined. Person Role Period; Brian Shin. Sirtris Pharmaceuticals has raised a total of $82M in funding over 4 rounds. Find 424 listings related to Sirtris Pharmaceuticals Inc in Cambridge on YP.com. Medvedik has worked as a biotechnology consultant at Sirtris Pharmaceuticals and has taught molecular and synthetic biology to hundreds of students while at Harvard University, The Cooper Union, School of Visual Arts, Genspace and NYU. Really? In most courses studied at Harvard Business schools, students are provided with a case study. The Pharmaceutical Industry And Health Professional Services. Living in the United States has Advantages over living in my country America- A country of Immigrants. Explore. [5] GSK paid $22.50/share, when Sirtris's stock was trading at $12/share, down 45% from its highest price of the previous year. "Sirtris Pharmaceuticals Living Healthier Longer" Essays and Research Papers . Sirtris Pharmaceuticals: Living Healthier, Longer Fortune, February 12, 2007. Dr. David Sinclair is co-founder of several biotechnology companies (Sirtris Pharmaceuticals, Genocea Biosciences, OvaScience, CohBar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others (most notably Shaklee). Health Centers; Information by Medical Specialty; Homepages; Health Websites; Buy Online Sirtris Pharmaceuticals Living Healthier Longer Case Study Solution & Analysis. [1][3] The company's initial product was called SRT501, and was a formulation of reservatrol. The report includes information on current developmental pipeline, complete with latest updates, and features on discontinued and dormant projects. Sirtris Pharmaceuticals, Inc. S. Sirtris Pharmaceuticals, Inc. Pathway-oriented platforms are rare, and dealmaking around them can be complicated: partner too early or for too little and you risk giving away the store. N9-808-112 MARCH 18, 2008 TOBY STUART DAVID KIRON Sirtris Pharmaceuticals: Living Healthier, Longer “You can live to be a hundred if you give up all the things that make you want to live to be a hundred. Sirtris’ focus to date has been on the development of SIRT1 activators for the treatment of Type 2 Diabetes Mellitus (T2DM). Sirtris Pharmaceuticals: Living Healthier, Longer by Toby Stuart , David Kiron , (No reviews yet) Write a Review By continuing to ... Use your energy where it's needed most — ensuring that your products are in compliance and … Their focus to date has been on the development of SIRT1 activators for the treatment of Type 2 Diabetes Mellitus (T2DM). Chemicals, Pharmaceuticals & Plastics. The deal is another example of Pharma's interest in platform biotechs and its hunger for innovation. SaaS, Android, Cloud Computing, Medical Device), Where the organization is headquartered (e.g. GSK is one of the largest pharmaceutical companies in the world, headquartered in London; it has significant products in both consumer and pharmaceutical areas. [4], Sirtris went public in 2007 and was subsequently purchased and made a subsidiary of GlaxoSmithKline in 2008 for $720 million. See Appendix for pictures of the covers of the Wall Street Journal and Fortune. Sirtris Pharmaceuticals has established a drug discovery capability to exploit sirtuin modulation for the treatment of human disease, an approach that has the potential to generate multiple clinically and commercially important products. "[18][19], "Tests Begin on Drugs That May Slow Aging", "Former Sirtris Execs' Nonprofit Starts Selling Resveratrol with Potential Anti-Aging Effects Online", "UPDATED: GSK moves to shutter Sirtris' Cambridge office, integrate R&D", "The Sirtris Compounds: Worthless? Sirtris Pharmaceuticals, Inc. was a biotechnology company based in Cambridge, MA that developed therapies for type 2 diabetes, cancer, and other diseases. Sirtris Pharmaceuticals, Inc. specializes in Pharmaceutical Preparations. Product Status Description; There are no products. But Sirtris pulled it off, via M&A, when GSK tendered a whopping $720 million for it in April. Sirtris Pharmaceuticals Inc., a biopharmaceutical company engaged in developing small molecule drugs that target the sirtuins, a recently discovered family of seven enzymes associated with the aging process, was acquired by GlaxoSmithKline (NYSE: GSK) in June of 2008 and now operates as the company’s wholly-owned subsidiary. GlaxoSmithKline acquires Sirtris Pharmaceuticals for approximately $720 million through a cash tender offer and merger of $22.50 per share, the firms state June 6. See Appendix for pictures of the covers of the Wall Street Journal and Fortune. 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