if you develop swelling in your feet, ankles, or hands, or unexplained weight gain contact your doctor as it may be a sign that your kidneys not working as well. Various medical organizations claimed that the discontinuation of antidepressants was not associated with significant withdrawal symptoms despite numerous complaints by patients that they experienced physical and psychological symptoms once these drugs were abruptly discontinued. Medicines that interact with losartan may either decrease its effect, affect how long it works for, increase side effects, or have less of an effect when taken with losartan. May be administered with other drugs that are also used to lower blood pressure (such as diuretics). antipsychotic agents (may enhance the blood pressure-lowering effect), such as aripiprazole or clozapine, NSAIDs, such as ibuprofen, diclofenac, or naproxen, other ARBs (such as candesartan or irbesartan) or ACE inhibitors (such as captopril or lisinopril), phosphodiesterase-5-inhibitors, such as sildenafil, sedatives, such as temazepam and zolpidem. These are some of the most common side effects: – Diarrhea: Some people may notice diarrhea immediately after stopping losartan. Visible Water Retention ... taking a beta blocker for hbp for about 6 months but have side effects dr told me to take losartan and stop beta safe to … We are able to test incoming & current patients as well as staff for coronavirus to ensure peace of mind and focus on addiction treatment. In the RENAAL study -- a premarketing study -- 14 percent of the 1,513 participants reported feelings of fatigue. Thus, losartan may be a drug that is prescribed to individuals with substance use disorders; however, there is no recognized literature that suggests that it is a significant drug of abuse itself, that its use fosters some other forms of drug abuse, or that it is a potential substance that individuals who are in recovery will use during relapse for its psychoactive effects. Copyright 1996-2021 Drugs.com. This randomized, double-blind, parallel-group, multicenter study compared the efficacy of amlodipine and losartan in an older hypertensive population, focusing on therapeutic coverage in the case of missed doses. 39 In rats with aortic coarctation, 2-week administration of losartan at a sub-antihypertensive dose of 3 mg/kg per day reduced ACE expression and ACE activity to the level of sham-operated animals, a mechanism that might also result in decreased bradykinin breakdown. This medication is available as an oral tablet and may also come with the brand name Cozaar on the label. Second, a direct effect of losartan on aortic ACE expression and activity has been suggested. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Losartan may be used for the treatment of high blood pressure or certain types of … But, if it is nearly time for your next dose, just take the next dose at the right time. Along with other … When pregnancy is detected, discontinue losartan as soon as possible. May be used to treat high blood pressure in adults and children over the age of six. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. This claim by various medical associations, including APA, continued for quite some time until a formal syndrome was identified as a result of the discontinuation of these medications in a small percentage of individuals. It is classified as an angiotensin II receptor agonist, and its use leads to blood vessels not constricting and lowered blood pressure. The appearance of physical and even psychological issues with the sudden discontinuation of losartan and not labeling them as a formal type of withdrawal syndrome is reminiscent of the denial by various medical associations regarding the discontinuation of antidepressant medications, which are drugs that are also not significant drugs of abuse like antihypertensive medications. May interact with a number of other drugs including NSAIDs, lithium, and potassium supplements. May be the preferred treatment in people with more than one type of heart condition. If you forget to take your dose, take it as soon as you remember that day. ... can i stop taking losartan abruptly. Laguna is taking every precaution to ensure patient and staff safety. Losartan belongs to a group of medicines known as angiotensin II receptor blockers (which may be shortened to ARBs). Diarrhea, tiredness, and low blood sugar have also reported in people with type 2 diabetes taking losartan. Losartan works on a hormone called angiotensin II to lower blood pressure and may also improve kidney function in some people. Stomach Cramps 10. At the current time, most sources do not refer to the symptoms that may result when an individual discontinues an antihypertensive medication like losartan as a form of withdrawal; however, the approach to controlling the symptoms is the same as the approach used to avoid withdrawal symptoms that are associated with many prescription medications. You should refer to the prescribing information for losartan for a complete list of interactions. Even though losartan is not a significant drug of abuse, any individual who has been taking the drug should only discontinue it under the supervision of a physician and according to their physician’s instructions. May also be used to improve kidney outcomes in the general population (excluding African-American people) without kidney disease. Losartan should never be administered with aliskiren. Following a 4-week, single-blind, placebo washout period, 211 patients were randomly as … Nonetheless, some of these issues include: Thus, when the drug is discontinued, it is typically done on a tapering schedule to wean the person off the medication and avoid these potential issues. Our editors and medical reviewers have over a decade of cumulative experience in medical content editing and have reviewed... © 2021 American Addiction Centers. Cozaar (losartan) is an antihypertensive medication. Losartan Side Effects In Summary. Talk to your doctor if this happens to you. Losartan isn't suitable for some people. Diarrhea 4. If a woman inadvertently becomes pregnant while taking losartan, it should be immediately discontinued. Action comes amid ongoing recall of other heart drugs, but patients cautioned to not stop taking their meds. Low Blood Sugar 8. It is typically prescribed to treat hypertension in a variety of situations, and it is effective for these uses. If you do experience side effects, talk to your doctor about ways to lessen the effects, or to stop taking the medication altogether. Losartan tablets may be made into a suspension for people who have difficulty swallowing. Should not be used during pregnancy. People whose renal function is dependant on the activity of the renin-angiotensin system (which includes the hormone angiotensin II), such as people with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or who are dehydrated are more at risk. Some people who take Losartan may experience side effects. Generic losartan/hctz is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Any side-effects are usually mild, and can include feeling dizzy or light-headed. View complete list of side effects. 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